Search on: CALMODULIN 
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Descriptor English:   Calmodulin 
Descriptor Spanish:   Calmodulina 
Descriptor Portuguese:   Calmodulina 
Synonyms English:   Calcium-Dependent Activator Protein
Calcium-Dependent Regulator  
Tree Number:   D12.644.360.381.249
D12.776.157.125.412.249
D12.776.476.387.249
Definition English:   A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The binding of calcium ions to this protein allows this protein to bind to cyclic nucleotide phosphodiesterases and to adenyl cyclase with subsequent activation. Thereby this protein modulates cyclic AMP and cyclic GMP levels. 
Indexing Annotation English:   a calcium-binding protein; /biosyn /physiol permitted
History Note English:   84; was CALCIUM-DEPENDENT REGULATOR see under CALCIUM-BINDING PROTEINS 1980-83; was CALCIUM-DEPENDENT REGULATOR see under CARRIER PROTEINS 1979 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   2180 
Unique Identifier:   D002147 

Occurrence in VHL:
 

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