Search on: INTERFERONS 
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Descriptor English:   Interferons 
Descriptor Spanish:   Interferones 
Descriptor Portuguese:   Interferons 
Tree Number:   D12.644.276.374.440
D12.644.276.718
D12.776.467.374.440
D12.776.467.718
D23.529.374.440
D23.529.718
Definition English:   Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. 
Indexing Annotation English:   "stimulators" or "inducers" = INTERFERON INDUCERS
Pharmacological Action:   Antineoplastic Agents
Antiviral Agents
 
See Related English:   Receptors, Interferon
 
History Note English:   83; was INTERFERON 1963-82 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   29469 
Unique Identifier:   D007372 

Occurrence in VHL:
 

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