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LEVODOPA
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DeCS
Descriptor
English
:
Levodopa
Descriptor
Spanish
:
Levodopa
Descriptor
Portuguese
:
Levodopa
Synonyms
English
:
L-Dopa
Tree Number:
D02.092.311.200.480
D12.125.072.050.685.400.500
D12.125.072.050.875.130.500
Definition
English
:
The naturally occurring form of
DIHYDROXYPHENYLALANINE
and the immediate precursor of
DOPAMINE
. Unlike
dopamine
itself, it can be taken orally and crosses the
blood-brain barrier
. It is rapidly taken up by dopaminergic
neurons
and converted to
DOPAMINE
. It is used for the treatment of
PARKINSONIAN DISORDERS
and is usually given with agents that inhibit its conversion to
dopamine
outside of the
central nervous system.
Pharmacological Action:
Antiparkinson Agents
Dopamine Agents
See Related
English
:
Dopamine
History Note
English
:
75; was see DOPA 1972-74
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
24230
Unique Identifier:
D007980
Occurrence in VHL
:
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