Search on: 1-METHYL-3-ISOBUTYLXANTHINE 
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Descriptor English:   1-Methyl-3-isobutylxanthine 
Descriptor Spanish:   1-Metil-3-Isobutilxantina 
Descriptor Portuguese:   1-Metil-3-Isobutilxantina 
Synonyms English:   3-Isobutyl-1-methylxanthine
Isobutyltheophylline  
Tree Number:   D03.438.759.758.824.751.500
Definition English:   A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES 
Indexing Annotation English:   DF: MIBX
Pharmacological Action:   Phosphodiesterase Inhibitors
 
History Note English:   91(79); was see under THEOPHYLLINE 1979-90 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   8950 
Unique Identifier:   D015056 

Occurrence in VHL: 		 

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