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5-HT
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DeCS
Descriptor
English
:
Serotonin
Descriptor
Spanish
:
Serotonina
Descriptor
Portuguese
:
Serotonina
Synonyms
English
:
5-HT
5-Hydroxytryptamine
Tree Number:
D02.092.211.215.801.852
D03.438.473.914.814
D23.469.050.650
Definition
English
:
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In
humans
it is found primarily in the
central nervous system
,
gastrointestinal tract
, and
blood platelets
.
Serotonin
mediates several important physiological functions including neurotransmission,
gastrointestinal motility
,
hemostasis
, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Indexing Annotation
English
:
/antag =
SEROTONIN ANTAGONISTS
but consider also
SEROTONIN UPTAKE INHIBITORS
Pharmacological Action:
Serotonin Agents
Entry Combination - descr/qualif
English
:
Serotonin
/
agonists
use
Serotonin Agonists
Serotonin
/
antagonists & inhibitors
use
Serotonin Antagonists
See Related
English
:
Receptors, Serotonin
Serotonin Agents
Serotonin Syndrome
History Note
English
:
HYDROXYTRYPTAMINE was see SEROTONIN 1975-92
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
24311
Unique Identifier:
D012701
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS