Search on: 5-OXOPROLYL-PEPTIDASE 
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Descriptor English:   Pyroglutamyl-Peptidase I 
Descriptor Spanish:   Piroglutamil-Peptidasa I 
Descriptor Portuguese:   Piroglutamil-Peptidase I 
Synonyms English:   Pyroglutamate Aminopeptidase
Pyrrolidonecarboxylate Peptidase
Pyrrolidonyl Peptidase
5-Oxoprolyl-Peptidase  
Tree Number:   D08.811.277.656.350.100.755
Definition English:   An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3. 
History Note English:   95: was 5-OXOPROLYL-PEPTIDASE 1991-94; was PYROGLUTAMATE AMINOPEPTIDASE see under AMINOPEPTIDASES 1975-90 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   29282 
Unique Identifier:   D011751 

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