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6-MERCAPTOPURINE
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DeCS
Descriptor
English
:
6-Mercaptopurine
Descriptor
Spanish
:
6-Mercaptopurina
Descriptor
Portuguese
:
6-Mercaptopurina
Tree Number:
D02.886.489.534
D03.438.759.534
Definition
English
:
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine
metabolism
and is used, usually in combination with other drugs, in the treatment of or in remission
maintenance
programs
for
leukemia.
Pharmacological Action:
Antimetabolites
Antimetabolites, Antineoplastic
Immunosuppressive Agents
Nucleic Acid Synthesis Inhibitors
History Note
English
:
85; was MERCAPTOPURINE 1963-84; ARABINOSYL-6-MERCAPTOPURINE was heading 1975-91 (see under 6-MERCAPTOPURINE 1975-90)
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
8800
Unique Identifier:
D015122
Occurrence in VHL
:
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