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DeCS
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Descriptor English:
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Phosphofructokinase-2
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Descriptor Spanish:
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Fosfofructoquinasa-2
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Descriptor Portuguese:
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Fosfofrutoquinase-2
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Synonyms English:
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6-Phosphofructo-2-Kinase
6-Phosphofructo-2-kinase-fructose-2,6-bisphosphatase
Fructose-2,6-Bisphosphatase
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Tree Number:
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D08.811.277.352.650.622
D08.811.913.696.620.225.850.750
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Definition English:
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An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate. |
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See Related English:
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Phosphofructokinase-1
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History Note English:
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2002; for 6-PHOSPHOFRUCTO-2-KINASE use PHOSPHOTRANSFERASES (NM) 1993-2001, use PHOSPHOTRANSFERASES, ATP (NM) 1981-1993; for FRUCTOSE-2,6-BISPHOSPATASE use PHOSPHORIC MONOESTER HYDROLASES (NM) 1983-2001; for 6-PHOSPHOFRUCTO-2-KINASE-FRUCTOSE-2,6-BISPHOSPHATASE use FRUCTOSE-BISPHOSPHATASE (NM) 1990-2001, use MULTIENZYME COMPLEXES (NM) 1990-2001, use PHOSPHOFRUCTOKINASE-1 (NM) 1990-2001
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Allowable Qualifiers English:
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Record Number:
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36081
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Unique Identifier:
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D025481
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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