Search on: ALPHA-AMANITIN 
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Descriptor English:   Alpha-Amanitin 
Descriptor Spanish:   Alfa-Amanitina 
Descriptor Portuguese:   Alfa-Amanitinas 
Tree Number:   D04.345.566.050.111
D12.644.456.050.111
D12.644.641.050.111
D23.946.587.175.111
Definition English:   A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. It inhibits RNA POLYMERASE II. Poisoning may require LIVER TRANSPLANTATION. 
Pharmacological Action:   Nucleic Acid Synthesis Inhibitors
Poisons
 
See Related English:   Mushroom Poisoning
 
History Note English:   2008; use AMANITINS 1980-2007 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects economics
genetics history
immunology isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects supply & distribution
standards toxicity
therapeutic use urine
Record Number:   52652 
Unique Identifier:   D053959 

Occurrence in VHL: 		 

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