Search on: CARDIOTOXINS 
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Descriptor English:   Cardiotoxins 
Descriptor Spanish:   Cardiotoxinas 
Descriptor Portuguese:   Cardiotoxinas 
Synonyms English:   Cardiotoxic Agents  
Tree Number:   D27.888.569.142
Definition English:   Agents that have a damaging effect on the HEART. Such damage can occur from ALKYLATING AGENTS; FREE RADICALS; or metabolites from OXIDATIVE STRESS and in some cases is countered by CARDIOTONIC AGENTS. Induction of LONG QT SYNDROME or TORSADES DE POINTES has been the reason for viewing some drugs as cardiotoxins. 
Indexing Annotation English:   do not confuse with CARDIOTONIC AGENTS
History Note English:   2008 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   52850 
Unique Identifier:   D054715 

Occurrence in VHL: 		 

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