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DeCS
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Descriptor English:
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Estradiol
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Descriptor Spanish:
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Estradiol
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Descriptor Portuguese:
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Estradiol
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Synonyms English:
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17 beta-Estradiol
Estradiol-17 beta
Oestradiol
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Tree Number:
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D04.808.365.415.248
D06.472.334.851.437.500
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Definition English:
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Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized. |
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Pharmacological Action:
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Estrogens
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Entry Combination - descr/qualif English:
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Estradiol/antagonists & inhibitors use Estradiol Antagonists
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See Related English:
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Receptors, Estradiol
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History Note English:
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63; for OVOCYCLIN use ESTRADIOL DIPROPIONATE (NM) 1980-98; /therapeutic use was ESTRADIOL, THERAPEUTIC 1965
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Allowable Qualifiers English:
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Record Number:
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5049
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Unique Identifier:
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D004958
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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