Search on: MESNA 
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Descriptor English:   Mesna 
Descriptor Spanish:   Mesna 
Descriptor Portuguese:   Mesna 
Synonyms English:   Coenzyme M
2-Mercaptoethanesulfonate  
Tree Number:   D02.455.326.146.100.050.490
D02.886.489.590
D02.886.645.600.055.050.500
Definition English:   A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE. 
Pharmacological Action:   Protective Agents
 
History Note English:   92; was 2-MERCAPTOETHANESULFONATE 1977-91 (see under MERCAPTOETHANOL 1977-90); MESNA was see 2-MERCAPTOETHANESULFONATE 1978-91 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   30385 
Unique Identifier:   D015080 

Occurrence in VHL: 		 

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