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PODOCYTES
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DeCS
Descriptor
English
:
Podocytes
Descriptor
Spanish
:
Podocitos
Descriptor
Portuguese
:
Podócitos
Synonyms
English
:
Visceral Epithelial Cells, Glomerular
Tree Number:
A05.810.453.324.359.720
A05.810.453.736.520.720
A11.436.720
Definition
English
:
Highly differentiated
epithelial cells
of the visceral layer of
BOWMAN CAPSULE
of the
KIDNEY
. They are composed of a cell body with major
CELL SURFACE EXTENSIONS
and secondary fingerlike extensions called pedicels. They enwrap the
KIDNEY GLOMERULUS
capillaries
with their
cell surface extensions
forming a
filtration
structure. The pedicels of neighboring
podocytes
interdigitate with each other leaving between them
filtration
slits that are bridged by an extracellular structure impermeable to large macromolecules called the slit
diaphragm
, and provide the last barrier to protein loss in the
KIDNEY.
History Note
English
:
2006
Allowable Qualifiers
English
:
chemistry
classification
cytology
drug effects
enzymology
immunology
metabolism
microbiology
pathology
physiology
parasitology
radiography
radiation effects
radionuclide imaging
secretion
transplantation
ultrastructure
ultrasonography
virology
Record Number:
50371
Unique Identifier:
D050199
Occurrence in VHL
:
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