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VENTURICIDINS
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DeCS
Descriptor
English
:
Venturicidins
Descriptor
Spanish
:
Venturicidinas
Descriptor
Portuguese
:
Venturicidinas
Tree Number:
D02.540.800
Definition
English
:
Toxic substances isolated from various strains of
Streptomyces
. They are 20-membered
macrolides
that inhibit
oxidative phosphorylation
and mitochondrial ATPases.
Venturicidins
A and B are
glycosides
. Used mainly as tools in the study of mitochondrial function.
Indexing Annotation
English
:
uncoupling agents & antifungal antibiotics; from
Streptomyces
Pharmacological Action:
Antibiotics, Antifungal
Uncoupling Agents
History Note
English
:
91(77); was see under LACTONES 1977-90
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
15103
Unique Identifier:
D014698
Occurrence in VHL
:
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