Search on: VIGABATRIN 
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Descriptor English:   Vigabatrin 
Descriptor Spanish:   Vigabatrin 
Descriptor Portuguese:   Vigabatrina 
Synonyms English:   gamma-Vinyl-gamma-Aminobutyric Acid  
Tree Number:   D02.241.081.160.050.350.900
D12.125.190.350.900
Definition English:   An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID. (From Martindale The Extra Pharmacopoeia, 31st ed) 
Pharmacological Action:   Anticonvulsants
Enzyme Inhibitors
GABA Agents
 
History Note English:   2000; use VIGABATRIN 1977-1999 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   34388 
Unique Identifier:   D020888 

Occurrence in VHL: 		 

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