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AMINO ACID CHLOROMETHYL KETONES
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DeCS
Descriptor
English
:
Amino Acid Chloromethyl Ketones
Descriptor
Spanish
:
Clorometilcetonas de Aminoácidos
Descriptor
Portuguese
:
Clorometilcetonas de Aminoácidos
Synonyms
English
:
Peptide Chloromethyl Ketones
Tree Number:
D12.125.065
Definition
English
:
Inhibitors of
SERINE ENDOPEPTIDASES
and sulfhydryl group-containing
enzymes
. They act as
alkylating agents
and are known to interfere in the translation process.
Indexing Annotation
English
:
serine proteinase inhib; DF: AACK
Pharmacological Action:
Alkylating Agents
Protein Synthesis Inhibitors
Serine Proteinase Inhibitors
History Note
English
:
77
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
594
Unique Identifier:
D000590
Occurrence in VHL
:
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