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ANTIBODIES, BLOCKING
Descriptors Found:
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DeCS
Descriptor
English
:
Antibodies, Blocking
Descriptor
Spanish
:
Anticuerpos Bloqueadores
Descriptor
Portuguese
:
Anticorpos Bloqueadores
Synonyms
English
:
Antibodies, Enhancing
Blocking Antibodies
Enhancing Antibodies
Tree Number:
D12.776.124.486.485.114.143
D12.776.124.790.651.114.143
D12.776.377.715.548.114.143
Definition
English
:
Antibodies that inhibit the reaction between ANTIGEN and other
antibodies
or sensitized
T-LYMPHOCYTES
(e.g.,
antibodies
of the
IMMUNOGLOBULIN G
class that compete with IGE
antibodies
for antigen, thereby blocking an allergic response). Blocking
antibodies
that bind tumors and prevent destruction of tumor
cells
by CYTOTOXIC
T-LYMPHOCYTES
have also been called enhancing
antibodies
. (Rosen et al.,
Dictionary
of Immunology, 1989)
Indexing Annotation
English
:
antibodies inhibiting reaction between antigen and other
antibodies
or sensitized
T-lymphocytes
: not for any antibody reaction to an antigen ( =
ANTIBODIES
or specific antibody); do not coordinate with
ANTIBODY FORMATION
for /biosyn
Pharmacological Action:
Immunologic Factors
History Note
English
:
96
Allowable Qualifiers
English
:
administration & dosage
adverse effects
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
poisoning
radiation effects
toxicity
therapeutic use
ultrastructure
urine
Record Number:
32855
Unique Identifier:
D019138
Occurrence in VHL
:
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