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ANTIGENS, CD15
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DeCS
Descriptor
English
:
Antigens, CD15
Descriptor
Spanish
:
Antígenos CD15
Descriptor
Portuguese
:
Antígenos CD15
Synonyms
English
:
Fucosyl SSEA-1
LE(X) Antigen
Lewis X Antigen
SSEA-1
SSEA-1 Determinant
Sialyl SSEA-1
Stage-Specific Embryonic Antigen-1
CD15 Antigens
Leu-M1 Antigens
Tree Number:
D09.400.410.420.025.060
D10.390.470.025.060
D10.570.877.360.025.060
D23.050.285.050.050
D23.050.301.264.035.115
D23.050.301.264.900.050
D23.050.550.325.050
D23.101.100.110.115
D23.101.100.900.050
D23.101.840.075.050
Definition
English
:
Carbohydrate antigen which is accumulated in various human cancer
tissues
and secreted into the
blood
stream. The carbohydrate moiety can be further modified with
fucose
or sialic acid. Monoclonal
antibodies
have been determined which can discriminate each subgroup of this antigen in the sera of cancer
patients
. Sialyl SSEA-1 antigen is particularly elevated in the sera of
patients
with a variety of tumors.
Indexing Annotation
English
:
do not coord FUCOSYL SSEA-1 or SIALYL SSEA-1 with
FUCOSE
or SIALIC ACID unless particularly discussed; DF: SSEA1
History Note
English
:
95; was STAGE-SPECIFIC EMBRYONIC ANTIGEN-1 1991-94; LEU-M1 ANTIGENS was see ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC 1989-94; CD15 ANTIGENS was CD15 ANTIGEN (NM) 1987-94; LEWIS X HAPTEN was NM 1987-94
Allowable Qualifiers
English
:
administration & dosage
adverse effects
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
contraindications
drug effects
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
poisoning
radiation effects
toxicity
therapeutic use
ultrastructure
urine
Record Number:
29130
Unique Identifier:
D016256
Occurrence in VHL
:
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