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AUTOCRINE MOTILITY FACTOR
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DeCS
Descriptor
English
:
Autocrine Motility Factor
Descriptor
Spanish
:
Factor de Motilidad Autocrina
Descriptor
Portuguese
:
Fator Autócrino de Motilidade
Synonyms
English
:
Tumor Autocrine Motility Factor
Tree Number:
D08.811.399.475.200.174
D12.644.276.374.050
D12.776.467.374.050
D12.776.624.050
D23.101.840.100
D23.529.374.050
Definition
English
:
A protein cytokine secreted by tumor
cells
. It elicits increases in cell motility and phosphoinositide
metabolism
in the secreting cell via a pertussis toxin-sensitive G-protein
signal transduction
pathway. It is closely related to PHOSPHOHEXOSE ISOMERASE;
NEUROLEUKIN
; and maturation factor.
History Note
English
:
92; was TUMOR AUTOCRINE MOTILITY FACTOR (NM) 1987-91
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
30246
Unique Identifier:
D016554
Occurrence in VHL
:
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