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DeCS
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Descriptor English:
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Baclofen
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Descriptor Spanish:
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Baclofeno
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Descriptor Portuguese:
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Baclofeno
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Synonyms English:
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Baclophen
Chlorophenyl GABA
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Tree Number:
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D02.241.081.160.050.350.100
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Definition English:
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A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist at GABA-B receptors (RECEPTORS, GABA-B). It is used in the treatment of spasticity, especially that due to spinal cord damage. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission. |
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Pharmacological Action:
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GABA Agonists
Muscle Relaxants, Central
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History Note English:
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80(75); was see under AMINOBUTYRIC ACIDS 1975-79
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Allowable Qualifiers English:
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Record Number:
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1442
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Unique Identifier:
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D001418
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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