Search on: BENSERAZIDE 
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Descriptor English:   Benserazide 
Descriptor Spanish:   Benserazida 
Descriptor Portuguese:   Benserazida 
Synonyms English:   Serazide
Seryltrihydroxybenzylhydrazine  
Tree Number:   D02.442.175
Definition English:   An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone. 
Pharmacological Action:   Antiparkinson Agents
Dopamine Agents
Enzyme Inhibitors
 
History Note English:   91(79); was see under HYDRAZINES 1979-90; was SERYLTRIHYDROXY BENZYLHYDRAZINE see under HYDRAZINES 1973-78 (Prov 1973-74) 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
history immunology
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
urine  
Record Number:   23953 
Unique Identifier:   D001545 

Occurrence in VHL:
 

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