Search on: BONE REPLACEMENT MATERIALS 
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Descriptor English:   Bone Substitutes 
Descriptor Spanish:   Substitutos de Huesos 
Descriptor Portuguese:   Substitutos Ósseos 
Synonyms English:   Bone Replacement Materials  
Tree Number:   D25.130.325
J01.637.051.130.325
Definition English:   Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue. 
Indexing Annotation English:   IM; coord with specific bone (IM) if relevant + substitute material (IM) if significant
History Note English:   95 
Allowable Qualifiers English:  
administration & dosage adverse effects
analysis chemistry
classification chemical synthesis
contraindications diagnostic use
economics history
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
Record Number:   32333 
Unique Identifier:   D018786 

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