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DeCS
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Descriptor English:
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Botulinum Toxins
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Descriptor Spanish:
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Toxinas Botulínicas
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Descriptor Portuguese:
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Toxinas Botulínicas
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Synonyms English:
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Botulin
Clostridium botulinum Toxins
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Tree Number:
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D12.776.097.156
D23.946.123.179
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Definition English:
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Proteins synthesized as a single chain of ~150 kDa with 35% sequence identity to TETANUS TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. They have neuro-, entero-, and hemotoxic properties, are immunogenic, and include the most potent poisons known. The most commonly used apparently blocks release of ACETYLCHOLINE at cholinergic SYNAPSES. |
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Indexing Annotation English:
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/antag permitted but consider also BOTULINUM ANTITOXIN
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Pharmacological Action:
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Anti-Dyskinesia Agents
Poisons
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See Related English:
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Botulism
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History Note English:
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78; was BOTULINUM TOXIN 1969-77 (Prov 1969-71)
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Allowable Qualifiers English:
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Record Number:
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1930
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Unique Identifier:
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D001905
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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