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DeCS
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Descriptor English:
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Antigens, CD3
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Descriptor Spanish:
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Antígenos CD3
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Descriptor Portuguese:
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Antígenos CD3
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Synonyms English:
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CD3 Antigens
CD3 Complex
T3 Antigens
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Tree Number:
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D23.050.301.264.035.103
D23.050.301.264.894.095
D23.101.100.110.103
D23.101.100.894.095
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Definition English:
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Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA). |
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Indexing Annotation English:
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T-lymphocyte differentiation antigens
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See Related English:
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Receptors, Antigen, T-Cell
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History Note English:
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93; was T3 ANTIGEN COMPLEX (NM) 1983-92; T3 ANTIGENS was see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92
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Allowable Qualifiers English:
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Record Number:
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30831
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Unique Identifier:
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D017252
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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