Search on: CD4 ANTIGENS 
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Descriptor English:   Antigens, CD4 
Descriptor Spanish:   Antígenos CD4 
Descriptor Portuguese:   Antígenos CD4 
Synonyms English:   CD4 Antigens
CD4 Molecule
T4 Antigens, T-Cell
CD4 Receptors
Receptors, CD4  
Tree Number:   D12.776.543.750.705.852.420.810.500
D12.776.543.750.925.700.025
D23.050.301.264.035.104
D23.050.301.264.894.100
D23.101.100.110.104
D23.101.100.894.100
Definition English:   55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120. 
Indexing Annotation English:   for hematodermic CD4/CD56 neoplasm use LYMPHOMA, NON-HODGKIN
See Related English:   CD4-CD8 Ratio
HIV Envelope Protein gp120
 
History Note English:   90; was CD4 ANTIGENS see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989 
Allowable Qualifiers English:  
administration & dosage adverse effects
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
contraindications drug effects
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology poisoning
radiation effects toxicity
therapeutic use ultrastructure
urine  
Record Number:   24525 
Unique Identifier:   D015704 

Occurrence in VHL: 		 

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