Search on: CYP1A1 
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Descriptor English:   Cytochrome P-450 CYP1A1 
Descriptor Spanish:   Citocromo P-450 CYP1A1 
Descriptor Portuguese:   Citocromo P-450 CYP1A1 
Synonyms English:   CYP1A1
Ethoxyresorufin O-Deethylase
EROD  
Tree Number:   D08.244.453.040.555
D08.811.682.690.708.170.040.332
D12.776.422.220.453.040.332
Definition English:   A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity. 
Indexing Annotation English:   do not confuse with other cytochrome P-450 CYP's
History Note English:   97; was ETHOXYRESORUFIN O-DEETHYLASE (NM) 1979-96 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   33008 
Unique Identifier:   D019363 

Occurrence in VHL:
 

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