Search on: CALCITONIN GENE-RELATED PEPTIDE 
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Descriptor English:   Calcitonin Gene-Related Peptide 
Descriptor Spanish:   Péptido Relacionado con Gen de Calcitonina 
Descriptor Portuguese:   Peptídeo Relacionado com Gene de Calcitonina 
Tree Number:   D12.644.400.097
D12.776.641.650.097
Definition English:   Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator. 
Indexing Annotation English:   DF: CGRP
Pharmacological Action:   Vasodilator Agents
 
See Related English:   Receptors, Calcitonin Gene-Related Peptide
 
History Note English:   90 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   24549 
Unique Identifier:   D015740 

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