Search on: CALCIUM LEUCOVORIN 
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Descriptor English:   Leucovorin 
Descriptor Spanish:   Leucovorina 
Descriptor Portuguese:   Leucovorina 
Synonyms English:   Calcium Leucovorin
Citrovorum Factor
Folinic Acid
N(5)-Formyltetrahydrofolate  
Tree Number:   D03.438.733.631.400.800.350.450
D08.211.840.300.500
Definition English:   The active metabolite of FOLIC ACID. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. 
Indexing Annotation English:   deficiency: coordinate LEUCOVORIN /defic (IM) with FOLIC ACID DEFICIENCY (IM)
Pharmacological Action:   Vitamin B Complex
 
History Note English:   90; was CITROVORUM FACTOR 1964-89 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   28238 
Unique Identifier:   D002955 

Occurrence in VHL: 		 

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