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CAPTOPRIL
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DeCS
Descriptor
English
:
Captopril
Descriptor
Spanish
:
Captopril
Descriptor
Portuguese
:
Captopril
Tree Number:
D12.125.072.401.623.270
Definition
English
:
A potent and specific inhibitor of
PEPTIDYL-DIPEPTIDASE A
. It blocks the conversion of
ANGIOTENSIN I
to
ANGIOTENSIN II
, a vasoconstrictor and important regulator of arterial
blood pressure
.
Captopril
acts to suppress the
RENIN-ANGIOTENSIN SYSTEM
and inhibits
pressure
responses to exogenous angiotensin.
Pharmacological Action:
Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
History Note
English
:
86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
23180
Unique Identifier:
D002216
Occurrence in VHL
:
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