Search on: CARCINOMA, MERKEL CELL 
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Descriptor English:   Carcinoma, Merkel Cell 
Descriptor Spanish:   Carcinoma de Células de Merkel 
Descriptor Portuguese:   Carcinoma de Célula de Merkel 
Synonyms English:   Merkel Cell Tumor  
Tree Number:   C04.557.465.625.650.240.325
C04.557.470.200.025.370.325
C04.557.580.625.650.240.325
Definition English:   A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245) 
Indexing Annotation English:   /blood supply /chem /second /secret /ultrastruct permitted; coord IM with SKIN NEOPLASMS (IM)
History Note English:   89; CARCINOMA, TRABECULAR was see CARCINOMA, MERKEL CELL 1992-93 
Allowable Qualifiers English:  
blood blood supply
cerebrospinal fluid chemistry
chemically induced classification
congenital complications
diet therapy diagnosis
drug therapy economics
ethnology embryology
enzymology epidemiology
etiology genetics
history immunology
metabolism microbiology
mortality nursing
pathology prevention & control
physiopathology parasitology
psychology radiography
rehabilitation radionuclide imaging
radiotherapy secondary
secretion surgery
therapy ultrastructure
urine ultrasonography
veterinary virology
Record Number:   23573 
Unique Identifier:   D015266 

Occurrence in VHL:
 

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