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CASPASE 1
Descriptors Found:
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DeCS
Descriptor
English
:
Caspase 1
Descriptor
Spanish
:
Caspasa 1
Descriptor
Portuguese
:
Caspase 1
Synonyms
English
:
Interleukin-1beta Converting Enzyme
ICE Protease
IL-1 beta-Converting Enzyme
Tree Number:
D08.811.277.656.300.215.126.550.100
D12.644.360.075.405.550.100
D12.776.476.075.405.550.100
Definition
English
:
A long pro-domain caspase that has specificity for the precursor form of
INTERLEUKIN-1BETA
. It plays a
role
in
INFLAMMATION
by catalytically converting the inactive
forms
of
CYTOKINES
such as
interleukin-1beta
to their active, secreted form.
Caspase 1
is referred as
interleukin-1beta
converting enzyme and is frequently abbreviated
ICE.
See Related
English
:
Apoptosis
Interleukin-1
History Note
English
:
99; use CASPASE 1 (NM) 1989-98
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
33827
Unique Identifier:
D020170
Occurrence in VHL
:
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