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DeCS
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Descriptor English:
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Antimicrobial Cationic Peptides
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Descriptor Spanish:
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Péptidos Catiónicos Antimicrobianos
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Descriptor Portuguese:
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Peptídeos Catiônicos Antimicrobianos
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Synonyms English:
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Cationic Antimicrobial Peptides
Microbicidal Cationic Proteins
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Tree Number:
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D12.644.050
D12.776.543.695.054
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Definition English:
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Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane. |
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Pharmacological Action:
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Anti-Infective Agents
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See Related English:
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Blood Bactericidal Activity
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History Note English:
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2001; use ANTIMICROBIAL CATIONIC PEPTIDES (NM) to search MICROBICIDAL CATIONIC PROTEINS 1981-2000
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Allowable Qualifiers English:
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Record Number:
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35329
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Unique Identifier:
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D023181
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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