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CDK2 PROTEIN KINASE
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclin-Dependent Kinase 2
Descriptor
Spanish
:
Quinasa 2 Dependiente de la Ciclina
Descriptor
Portuguese
:
Quinase 2 Dependente de Ciclina
Synonyms
English
:
Cdk2 Protein Kinase
Tree Number:
D08.811.913.696.620.682.700.200.323
D08.811.913.696.620.682.700.646.500.750
D12.644.360.250.323
D12.776.167.200.323
D12.776.476.250.323
Definition
English
:
A key regulator of
CELL CYCLE
progression. It partners with
CYCLIN E
to regulate entry into
S PHASE
and also interacts with
CYCLIN A
to phosphorylate
RETINOBLASTOMA PROTEIN
. Its activity is inhibited by
CYCLIN-DEPENDENT KINASE INHIBITOR P27
and
CYCLIN-DEPENDENT KINASE INHIBITOR P21.
History Note
English
:
2006(1991)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
50714
Unique Identifier:
D051357
Occurrence in VHL
:
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