Search on: CDK4 PROTEIN KINASE 
Descriptors Found: 1
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Descriptor English:   Cyclin-Dependent Kinase 4 
Descriptor Spanish:   Quinasa 4 Dependiente de la Ciclina 
Descriptor Portuguese:   Quinase 4 Dependente de Ciclina 
Synonyms English:   Cdk4 Protein Kinase  
Tree Number:   D08.811.913.696.620.682.700.200.451
D08.811.913.696.620.682.700.646.500.875
D12.644.360.250.451
D12.776.167.200.451
D12.776.476.250.451
Definition English:   Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16. 
History Note English:   2006(1992) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   50715 
Unique Identifier:   D051358 

Occurrence in VHL: 		 

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