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DeCS
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Descriptor English:
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Paraneoplastic Cerebellar Degeneration
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Descriptor Spanish:
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Degeneración Cerebelar Paraneoplásica
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Descriptor Portuguese:
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Degeneração Paraneoplásica Cerebelar
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Synonyms English:
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Cerebellar Degeneration, Paraneoplastic
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
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Tree Number:
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C04.588.614.550.650
C04.730.856.650
C10.228.140.252.620
C10.574.781.700
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Definition English:
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Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686) |
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Indexing Annotation English:
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coord with precoord organ/neopl term + histol type
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History Note English:
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2000
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Allowable Qualifiers English:
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Record Number:
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34185
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Unique Identifier:
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D020362
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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