Search on: CHALONES 
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Descriptor English:   Chalones 
Descriptor Spanish:   Chalonas 
Descriptor Portuguese:   Calônios 
Tree Number:   D12.644.456.270
Definition English:   Peptides that inhibit mitosis (ANTIMITOTICS). During the 1960's the term referred to crude extracts that inhibited cell proliferation; the activity was later attributed to PYROGLUTAMATE type oligopeptides. 
Indexing Annotation English:   do not confuse with CHALCONES
History Note English:   2006, 1969-1992; use GROWTH INHIBITORS 1993-2005 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   50818 
Unique Identifier:   D050150 

Occurrence in VHL:
 

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