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CHIMERIN 1
Descriptors Found:
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DeCS
Descriptor
English
:
Chimerin 1
Descriptor
Spanish
:
Quimerina 1
Descriptor
Portuguese
:
Quimerina 1
Synonyms
English
:
alpha-Chimerin
alpha-1 Chimerin
alpha-2 Chimerin
arhGAP2 Protein
n-Chimerin
rhoGAP2 Protein
Tree Number:
D12.644.360.325.150.100.200
D12.776.402.150.100.200
D12.776.476.325.150.100.200
D12.776.641.124.200
Definition
English
:
A GTPase activating protein that is specific for
RAC GTP-BINDING PROTEINS
. It is expressed primarily in the
brain
and may be involved in
signal transduction
. The alternatively spliced form of
CHIMERIN 1
(alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the
brain
and testes.
History Note
English
:
2000; use CHIMERIN 1 (NM) 1990-1999; for ALPHA1-CHIMAERIN use GTPASE-ACTIVATING PROTEINS (NM) 1996-1999
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
34484
Unique Identifier:
D020848
Occurrence in VHL
:
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