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CHLORIMIPRAMINE
Descriptors Found:
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DeCS
Descriptor
English
:
Clomipramine
Descriptor
Spanish
:
Clomipramina
Descriptor
Portuguese
:
Clomipramina
Synonyms
English
:
Chlorimipramine
Tree Number:
D03.494.240.194
Definition
English
:
A tricyclic antidepressant
similar
to
IMIPRAMINE
that selectively inhibits the uptake of
serotonin
in the
brain
. It is readily absorbed from the
gastrointestinal tract
and demethylated in the
liver
to form its primary active metabolite, desmethylclomipramine.
Pharmacological Action:
Antidepressive Agents, Tricyclic
Serotonin Uptake Inhibitors
History Note
English
:
80(75); was CHLORIMIPRAMINE see under DIBENZAZEPINES 1968-79
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
3022
Unique Identifier:
D002997
Occurrence in VHL
:
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