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CHLORMETHIAZOLE
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DeCS
Descriptor
English
:
Chlormethiazole
Descriptor
Spanish
:
Clormetiazol
Descriptor
Portuguese
:
Clormetiazol
Tree Number:
D02.886.675.180
D03.383.129.708.180
Definition
English
:
A sedative and anticonvulsant often used in the treatment of alcohol withdrawal.
Chlormethiazole
has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate
GAMMA-AMINOBUTYRIC ACID
receptors response and it may also
affect
glycine
receptors.
Pharmacological Action:
Anticonvulsants
GABA Modulators
Hypnotics and Sedatives
Neuroprotective Agents
History Note
English
:
68; CHLORETHIAZOLE was see CHLORMETHAZOLE 1975-95
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
2764
Unique Identifier:
D002719
Occurrence in VHL
:
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