Search on: CHOLIC ACIDS 
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Descriptor English:   Cholic Acids 
Descriptor Spanish:   Ácidos Cólicos 
Descriptor Portuguese:   Ácidos Cólicos 
Synonyms English:   Cholalic Acids  
Tree Number:   D04.808.105.225
D04.808.221.430
Definition English:   The 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. They act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics. 
Indexing Annotation English:   cholic acid glycine conjugate = GLYCOCHOLIC ACID; cholic acid taurine conjugate = TAUROCHOLIC ACID; CHOLIC ACID is also available
Pharmacological Action:   Gastrointestinal Agents
 
History Note English:   75; was CHOLIC ACID 1973-74 (Prov 1973), was CHOLIC ACID see under BILE ACIDS AND SALTS 1963-73 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   2843 
Unique Identifier:   D002793 

Occurrence in VHL: 		 

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