Search on: CHROMOGRANINS 
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Descriptor English:   Chromogranins 
Descriptor Spanish:   Cromograninas 
Descriptor Portuguese:   Cromograninas 
Synonyms English:   Secretogranins  
Tree Number:   D12.776.641.199
D12.776.811.185
Definition English:   A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources. 
History Note English:   1991(1973) 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   2913 
Unique Identifier:   D002864 

Occurrence in VHL:
 

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