Search on: CITRATE CLEAVAGE ENZYME 
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Descriptor English:   ATP Citrate (pro-S)-Lyase 
Descriptor Spanish:   ATP Citrato (pro-S)-Liasa 
Descriptor Portuguese:   ATP Citrato (pro-S)-Liase 
Synonyms English:   Citrate Cleavage Enzyme
ATP Citrate Lyase
ATP Citrate Synthase  
Tree Number:   D08.811.913.050.331
Definition English:   An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8. 
History Note English:   98(73) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   1282 
Unique Identifier:   D001275 

Occurrence in VHL:
 

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