Search on: CLEAVAGE STIMULATION FACTOR 
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Descriptor English:   Cleavage Stimulation Factor 
Descriptor Spanish:   Factor de Estimulación del Desdoblamiento 
Descriptor Portuguese:   Fator Estimulador de Clivagem 
Tree Number:   D12.776.157.725.124.249
D12.776.664.962.444.249
Definition English:   A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction. 
History Note English:   2003; for CLEAVAGE STIMULATION FACTOR use MRNA CLEAVAGE AND POLYADENYLATION FACTORS (NM) 1992-2002 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   37404 
Unique Identifier:   D039241 

Occurrence in VHL:
 

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