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CO-DERGOCRINE
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DeCS
Descriptor
English
:
Dihydroergotoxine
Descriptor
Spanish
:
Dihidroergotoxina
Descriptor
Portuguese
:
Diidroergotoxina
Synonyms
English
:
Co-Dergocrine
Ergot Alkaloids, Hydrogenated
Tree Number:
D03.132.327.412.250
D03.549.562.400
Definition
English
:
A mixture of three different hydrogenated derivatives of
ERGOTAMINE
:
DIHYDROERGOCORNINE
;
DIHYDROERGOCRISTINE
; and
DIHYDROERGOCRYPTINE
.
Dihydroergotoxine
has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a
dopamine
agonist. The methanesulfonate
salts
of this mixture of
alkaloids
are called
ERGOLOID MESYLATES.
Pharmacological Action:
Adrenergic alpha-Antagonists
Dopamine Agonists
See Related
English
:
Dihydroergocornine
Dihydroergocristine
Dihydroergocryptine
History Note
English
:
1977(1975); for ERGOT ALKALOIDS, HYDROGENATED use ERGOLOID MESYLATES 1992-2001
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
4128
Unique Identifier:
D004088
Occurrence in VHL
:
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