Search on: COMPLEMENT C3 CONVERTASE, ALTERNATIVE PATHWAY 
Descriptors Found: 1
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Descriptor English:   Complement C3 Convertase, Alternative Pathway 
Descriptor Spanish:   Convertasa del Complemento C3 de la Vía Alternativa 
Descriptor Portuguese:   Convertase do Complemento C3 da Via Alternativa 
Tree Number:   D12.776.124.486.274.045.387.500.374
Definition English:   A serine protease that is the complex of COMPLEMENT C3B and COMPLEMENT FACTOR BB. It cleaves multiple COMPLEMENT C3 into COMPLEMENT C3A (anaphylatoxin) and COMPLEMENT C3B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   2006 (1989); for CVFBB use COMPLEMENT FACTOR B 1985-2005 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   50830 
Unique Identifier:   D051561 

Occurrence in VHL: 		 

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