Search on: COMPLEMENT C4B-BINDING PROTEIN 
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Descriptor English:   Complement C4b-Binding Protein 
Descriptor Spanish:   Proteína de Unión al Complemento C4b 
Descriptor Portuguese:   Proteína de Ligação ao Complemento C4b 
Tree Number:   D12.776.124.486.274.920.662
Definition English:   A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a). 
Pharmacological Action:   Complement Inactivating Agents
 
History Note English:   2006 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   50837 
Unique Identifier:   D050716 

Occurrence in VHL: 		 

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