Search on: COMPLEMENT C5 CONVERTASE, ALTERNATIVE PATHWAY 
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Descriptor English:   Complement C5 Convertase, Alternative Pathway 
Descriptor Spanish:   Convertasa del Complemento C5 de la Vía Alternativa 
Descriptor Portuguese:   Convertase do Complemento C5 da Via Alternativa 
Tree Number:   D12.776.124.486.274.045.387.500.750
Definition English:   A serine protease that cleaves multiple COMPLEMENT C5 into COMPLEMENT C5A (anaphylatoxin) and COMPLEMENT C5B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. It is the complex of ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) with an additional COMPLEMENT C3B, or C3bBb3b. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   2006 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   50831 
Unique Identifier:   D051566 

Occurrence in VHL: 		 

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