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Descriptor English:   Chelating Agents 
Descriptor Spanish:   Agentes Quelantes 
Descriptor Portuguese:   Quelantes 
Synonyms English:   Complexons
Metal Antagonists  
Tree Number:   D27.505.519.249
D27.720.222
Definition English:   Organic chemicals that form two or more coordination bonds with a central metal ion. Heterocyclic rings are formed with the central metal atom as part of the ring. Some biological systems form metal chelates, e.g., the iron-binding porphyrin group of hemoglobin and the magnesium-binding chlorophyll of plants. (From Hawley's Condensed Chemical Dictionary, 12th ed) They are used chemically to remove ions from solutions, medicinally against microorganisms, to treat metal poisoning, and in chemotherapy protocols. 
Indexing Annotation English:   D25-26 qualif; coord IM with specific chelating agent (IM) + metal being chelated (IM)
See Related English:   Antidotes
Iron Chelating Agents
 
History Note English:   HEAVY METAL DETOXICANTS was heading 1963-65 
Allowable Qualifiers English:  
administration & dosage adverse effects
analysis chemistry
classification chemical synthesis
contraindications diagnostic use
economics history
isolation & purification metabolism
pharmacology pharmacokinetics
poisoning radiation effects
supply & distribution standards
toxicity therapeutic use
Record Number:   2659 
Unique Identifier:   D002614 

Occurrence in VHL:
 

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