Search on:
CONDUCTION-BLOCKING ANESTHETICS
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Anesthetics, Local
Descriptor
Spanish
:
Anestésicos Locales
Descriptor
Portuguese
:
Anestésicos Locais
Synonyms
English
:
Anesthetics, Conduction-Blocking
Conduction-Blocking Anesthetics
Tree Number:
D27.505.696.277.100.200
D27.505.696.663.850.025
D27.505.954.427.210.100.200
Definition
English
:
Drugs that block nerve
conduction
when applied locally to
nerve tissue
in appropriate concentrations. They act on any part of the
nervous system
and on every type of nerve fiber. In contact with a nerve trunk, these
anesthetics
can cause both sensory and motor
paralysis
in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of
Therapeutics
, 8th ed) Nearly all local
anesthetics
act by reducing the tendency of voltage-dependent
sodium channels
to activate.
Indexing Annotation
English
:
see note at
ANESTHETICS
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
history
immunology
isolation & purification
metabolism
pharmacology
pharmacokinetics
poisoning
radiation effects
supply & distribution
standards
toxicity
therapeutic use
urine
Record Number:
790
Unique Identifier:
D000779
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS