Search on: CORE BINDING FACTOR ALPHA PROTEINS 
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Descriptor English:   Core Binding Factor alpha Subunits 
Descriptor Spanish:   Subunidades alfa del Factor de Unión al Sitio Principal 
Descriptor Portuguese:   Subunidades alfa de Fatores de Ligação ao Core 
Synonyms English:   Core Binding Factor alpha Proteins  
Tree Number:   D12.776.930.155.200
Definition English:   A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression. 
History Note English:   2006(1987) 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   51175 
Unique Identifier:   D050657 

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